First published article on genome editing in human embryos

Most other media sources have a bias on the impact and implications of the recent publication CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes by Liang et al.. If you want to read to yourself, you can download the PDF for free.

In short, the group tested the CRISPR/Cas9 genome engineering tools in non-viable human zygotes.

They discovered that their genome editing occurred at low efficiency, their intended target suffered repair from a endogenous sequence (a similar sequence on another part of the human genome) rather than using their donor oligos (synthetic DNA supplied to direct the intended mutation), and off-target mutation was observed. This is the first published article on genome editing in a model that is directly applicable to human health. This technology has been used in other organisms. The problems describe highlight the need to improve efficiency and specificity if this technology is ever going to have practical use.

How to Refresh Thumbnails on Google Chrome New Tab Page

In brief, for Windows 7: If you want to refresh the thumbnails shown on your Chrome browser New Tab page for your most visited sites, you can point your Run command or navigate your Explorer to the address:

%LOCALAPPDATA%\Google\Chrome\User Data\Default\

Then delete the file named "Top Sites." You will need to close Chrome when you are deleting it. When you re-open Chrome and open a New Tab, the thumbnails will be missing, but if you re-visit the pages, the thumbnails will repopulate.

The page at howtogeek.com describes how to do it for older versions of Chrome, but in the most recent version of Chrome (as of this posting on Windows Version 42.0.2311.90 m), the file you need to delete is "Top Sites" not "Thumbnails." This will probably also be the solution for other operating systems (Mac, Ubuntu, etc.).