10/31/2012

Final word

Today I had jury duty summons. Great experience. My questioning by the judge in the screening process led to rather heated debate, and at the end came down to him pointing out that I needed to leave my knowledge at the door and allow the expert to be the sole purveyor of interpretation of the data from the breathalizer.

(Judge's words:) "We have to all have reasonable trust in the expert when he tells us results from the tool... err... uhh... uhh... what's the word I'm looking for? Umm..." to which after several seconds I just jumped in and stated my last word in the courtroom, finishing his sentence, "instrument?"

I was promptly thanked and excluded from the jury by the prosecutors.

9/20/2012

Gene silencing in E coli with small RNAs

Sharma et. al describe a strategy to identify small RNAs that effect bacterial gene regulation, much like siRNA in mammalian systems. The authors write: "We anticipate that the artificial sRNAs will be useful for dynamic control and fine-tuning of endogenous gene expression in bacteria for applications in synthetic biology."

This could definitely save time when testing perturbations in bacterial metabolism to synthesize new products, enabling testing of hypotheses before the need for genome manipulation.

Read the abstract (or article if you have access) here: http://pubs.acs.org/doi/abs/10.1021/sb200001q

6/08/2012

Childhood Angst

Found outside my apt. I believe it reads "Why?" It's a good question.